您现在的位置:澳门mgm美高梅网站 > 教师名录

导师代码:11881

导师姓名:魏鑫

性  别:

出生年月:1984年11月

特  称:

职  称:副教授

学  位:博士

属  性:专职

电子邮件:weixin1120@uestc.edu.cn

2010/8 - 2014/8,美国内布拉斯加医学中心,药剂学,博士。 2007/9 - 2010/6,四川大学生物治疗国家重点实验室,细胞生物学,硕士。 2003/9 - 2007/7,四川大学,生物技术,学士
学术经历:
电子科技大学,医学院,副教授。长期从事肿瘤和靶向治疗相关的药剂学、药理学研究。参与国内外多个重大科研项目(科技部863“生物治疗关键技术与相关产品的规模化制备” 2007AA021201;十一五国家科技重大专项---国家重大新药创制“天然活性产物分离及分析关键技术” 2009ZX09501-015;十一五国家科技重大专项---国家重大新药创制“新型PI3Kγ抑制剂治疗重症肝炎一类新药SKLB010 的开发” 2009ZX09102-045, 美国NIH研究项目R01CA136921等)并取得了重要的学术成果。在多个高水平SCI杂志上发表学术论文11篇,引用次数200余次。
个人概况:
1. 脑部靶向性纳米药物载体的设计与研究 2. 针对耐药性肿瘤的新型靶向纳米药物的研究
科研项目:
1. Wei X, Senanayake TH, Warren G, Vinogradov SV. Hyaluronic acid-based nanogel-drug conjugates with enhanced anticancer activity designed for the targeting of CD44-positive and drug-resistant tumors. Bioconjug Chem. 2013;24(4):658-68. 2. Wei X, Senanayake TH, Bowling A, Vinogradov S. Targeted nanogel conjugate for improved stability and cellular permeability of curcumin: synthesis, pharmacokinetics and tumor growth inhibition. Mol. Pharmaceutics. 2014;11(9):3112-22. 3. Wei X, Senanayake TH, Vinogradov S. Overcoming drug resistant cancer by hyaluronic acid based nanogel formulated with anticancer drugs. Clinical Cancer Research 2012;18 (10 Supp), B60-B60. 4. Wei X, Han J, Chen ZZ, Qi BW, Wang GC, Ma YH, Zheng H, Luo YF, Wei YQ, Chen LJ. A phosphoinositide 3-kinase-gamma inhibitor, AS605240 prevents bleomycin-induced pulmonary fibrosis in rats. Biochem Biophys Res Commun. 2010; 397(2):311-7. 5. Zhong Z*, Wei X*, Qi B, Xiao W, Yang L, Wei Y, Chen L. A novel liposomal vaccine improves humoral immunity and prevents tumor pulmonary metastasis in mice. Int J Pharm. 2010; 399(1-2):156-62. (*co-first authors) 6. Vinogradov S, Wei X. Cancer stem cells and drug resistance: the potential of nanomedicine. Nanomedicine (Lond). 2012;7(4):597-615. 7. Senanayake TH, Warren G, Wei X, Vinogradov SV. Application of activated nucleoside analogs for the treatment of drug-resistant tumors by oral delivery of nanogel-drug conjugates. J Control Release. 2013;167(2):200-9. 8. Vinogradov S, Warren G, Wei X. Macrophages associated with tumors as potential targets and therapeutic intermediates. Nanomedicine (Lond). 2014;9:695-707. 9. Baowen Q, Yulin Z, Xin W, Wenjing X, Hao Z, Zhizhi C, Xingmei D, Xia Z, Yuquan W, Lijuan C. A further investigation concerning correlation between anti-fibrotic effect of liposomal quercetin and inflammatory cytokines in pulmonary fibrosis. Eur J Pharmacol. 2010; 642(1-3):134-9. 10. Ma Y, Wang X, Wu X, Wei X, Ma L, Zheng H, Qi B, Zhu W, Luo Y, Wei Y, Chen L. (Z)-5-(4-methoxybenzylidene) thiazolidine-2, 4-dione ameliorates the adjuvant-induced arthritis via inhibiting the migration of macrophage and down-regulating the cytokine mRNA expression. Int Immunopharmacol. 2010; 10(11):1456-62. 11. Hou W, Li Y, Zhang Q, Wei X, Peng A, Chen L, Wei Y Triterpene acids isolated from Lagerstroemia speciosa leaves as alpha-glucosidase inhibitors. Phytother Res. 2009; 23(5):614-8.
发表文章:

硕士招生专业

105500 药物研究与转化

02方向: 药物研究与转化

博士招生专业

XML 地图 | Sitemap 地图